Jan-Willem C Alffenaar Selected Research

2- ethylidene- 1,5- dimethyl- 3,3- diphenylpyrrolidine

4/2014	Fast and highly selective LC-MS/MS screening for THC and 16 other abused drugs and metabolites in human hair to monitor patients for drug abuse.
2/2014	Application of sweat patch screening for 16 drugs and metabolites using a fast and highly selective LC-MS/MS method.

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Jan-Willem C Alffenaar Research Topics

Disease

41	Tuberculosis (Tuberculoses) 10/2022 - 08/2010
24	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2020 - 02/2010
12	Extensively Drug-Resistant Tuberculosis 01/2021 - 08/2010
9	Critical Illness (Critically Ill) 01/2022 - 02/2008
9	Infections 01/2022 - 06/2009
6	Inflammation (Inflammations) 01/2022 - 12/2014
6	Mycoses (Diseases, Fungus) 12/2021 - 05/2009
5	Invasive Candidiasis 01/2022 - 11/2014
3	Body Weight (Weight, Body) 01/2022 - 12/2014
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 10/2019
3	Chemical and Drug Induced Liver Injury 01/2022 - 10/2018
3	Neoplasms (Cancer) 11/2021 - 12/2014
2	Asthma (Bronchial Asthma) 01/2022 - 01/2022
2	Candidiasis (Moniliasis) 01/2022 - 01/2014
2	Vomiting 01/2022 - 12/2015
2	Pulmonary Tuberculosis 07/2021 - 01/2021
2	Drug-Related Side Effects and Adverse Reactions 12/2019 - 07/2014
2	Diabetes Mellitus 10/2019 - 01/2019
2	Aspergillosis 08/2019 - 04/2016
2	Thrombocytopenia (Thrombopenia) 06/2017 - 02/2010
2	Invasive Fungal Infections 04/2016 - 12/2013
2	Substance-Related Disorders (Drug Abuse) 04/2014 - 02/2014
2	Peripheral Nervous System Diseases (PNS Diseases) 08/2010 - 02/2010
1	Paralysis (Palsy) 01/2022
1	Polyneuropathies (Polyneuropathy) 01/2022
1	Hypersensitivity (Allergy) 01/2022
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022
1	Muscular Diseases (Myopathy) 01/2022
1	Lung Injury 01/2022
1	Meningeal Tuberculosis (Tuberculous Meningitis) 01/2022
1	Nausea 01/2022
1	Hemolysis 11/2020
1	Breakthrough Infections 01/2020
1	Respiratory Syncytial Virus Infections 01/2020
1	Opportunistic Infections (Opportunistic Infection) 01/2020

Drug/Important Bio-Agent (IBA)

41	Pharmaceutical PreparationsIBA 10/2022 - 02/2010
12	Linezolid (Zyvox)FDA Link 01/2020 - 02/2010
9	Rifampin (Rifampicin)FDA LinkGeneric 10/2022 - 06/2009
9	Voriconazole (Vfend)FDA LinkGeneric 01/2020 - 02/2008
8	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 08/2015
6	Moxifloxacin (Avelox)FDA Link 01/2019 - 04/2010
5	Pyrazinamide FDA LinkGeneric 10/2022 - 11/2018
5	Fluconazole (Zonal)FDA LinkGeneric 01/2022 - 05/2009
5	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 01/2015
5	posaconazole FDA Link 08/2019 - 05/2009
5	Levofloxacin (Levaquin)FDA Link 01/2019 - 10/2016
4	Ribavirin (Virazole)FDA LinkGeneric 12/2020 - 01/2019
4	Carbapenems (Carbapenem Antibiotics)IBA 01/2019 - 04/2016
3	bedaquiline (R207910)IBA 01/2020 - 09/2015
3	Clarithromycin (Biaxin)FDA LinkGeneric 01/2017 - 06/2009
3	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 11/2015 - 08/2013
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2020
2	Antifungal AgentsIBA 11/2021 - 11/2014
2	Cycloserine (Seromycin)FDA Link 01/2020 - 11/2018
2	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2019 - 01/2017
2	Amikacin (A.M.K)FDA LinkGeneric 11/2018 - 01/2018
2	FluoroquinolonesIBA 01/2018 - 01/2017
2	C-Reactive ProteinIBA 01/2017 - 12/2014
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 05/2016
2	Ertapenem (Invanz)FDA Link 01/2017 - 04/2016
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2017 - 12/2014
2	Anidulafungin FDA Link 02/2015 - 01/2014
2	benzoylecgonineIBA 04/2014 - 02/2014
2	2- ethylidene- 1,5- dimethyl- 3,3- diphenylpyrrolidineIBA 04/2014 - 02/2014
2	Amphetamine (Amfetamine)FDA LinkGeneric 04/2014 - 02/2014
2	Cocaine (Cocaine HCl)IBA 04/2014 - 02/2014
2	Codeine (Codeine Phosphate)FDA LinkGeneric 04/2014 - 02/2014
2	CotinineIBA 04/2014 - 02/2014
2	Heroin (Diamorphine)IBA 04/2014 - 02/2014
2	Methadone (Dolophine)FDA LinkGeneric 04/2014 - 02/2014
2	Methamphetamine (Desoxyn)FDA LinkGeneric 04/2014 - 02/2014
2	Methylphenidate (Ritalin)FDA LinkGeneric 04/2014 - 02/2014
2	Morphine (MS Contin)FDA LinkGeneric 04/2014 - 02/2014
2	Nicotine FDA Link 04/2014 - 02/2014
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	GlucocorticoidsIBA 01/2022
1	Ganciclovir (Cytovene)FDA LinkGeneric 01/2022
1	CreatinineIBA 01/2022
1	Antitubercular AgentsIBA 01/2022
1	NitroimidazolesIBA 12/2020
1	OPC-67683IBA 12/2020
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 12/2020
1	Prothionamide (Protionamide)IBA 11/2020
1	Vancomycin FDA LinkGeneric 01/2020
1	LactamsIBA 01/2020
1	beta Lactam AntibioticsIBA 01/2020
1	AminoglycosidesIBA 01/2020
1	Doxycycline (Periostat)FDA LinkGeneric 01/2020
1	desacetylcefotaximeIBA 01/2020
1	TeicoplaninIBA 01/2020

Therapy/Procedure

9	Therapeutics 01/2022 - 02/2014
4	Drug Therapy (Chemotherapy) 01/2020 - 12/2015
3	Critical Care (Surgical Intensive Care) 01/2022 - 01/2020
3	Duration of Therapy 01/2018 - 03/2014
2	Polypharmacy 10/2019 - 09/2018
1	Medical Day Care (Partial Hospitalization) 01/2022
1	Artificial Respiration (Mechanical Ventilation) 01/2022
1	Mechanical Ventilators (Ventilator) 01/2022
1	Length of Stay 01/2022
1	Drug Tapering 01/2020